Salicylic acid binds NPR3 and NPR4 to regulate NPR1-dependent defense responses

• 来源期刊: 细胞研究（英文版）
• 年，卷（期）: 2012,（12）
• 页码范围: 1631-1633
• 页数: 3页
• 语种: 英文
• DOI: 10.1038/cr.2012.100

摘要

Salicylic acid(SA)is widely recognized as a key player in plant immunity.While several proteins have been previously identified as the direct targets of SA,SA-mediated plant defense signaling mechanisms remain unclear.The Nature paper from Xinnian Dong's group demonstrates that the NPR1 paralogues NPR3 and NPR4 directly bind SA,and this binding modulates their interaction with NPR1 and thereby degradation of this key positive regulator of SA-mediated defense,shedding important new insight into the mechanism(s)of SA-mediated,NPR1-dependent plant defense signal transduction.