Generation of dopaminergic neurons directly from mouse fibroblasts and fibroblast-derived neural progenitors

• 来源期刊: 细胞研究（英文版）
• 年，卷（期）: 2012,（4）
• 页码范围: 769-772
• 页数: 4页
• 语种: 英文
• DOI: 10.1038/cr.2012.32

摘要

Dear Editor,Parkinson's disease (PD) is a neurodegenerative disease that afflicts around 1％ of the population over age 65 [1].One of the pathological hallmarks of PD is the degeneration of dopaminergic (DA) neurons at midbrain and the relatively focal lesion feature of PD makes cell replacement a promising approach for treating the disease [2].