Efficient CAN catalyzed synthesis of 1H-indazolo[1,2-b] phthalazine-1,6,11-triones:An eco-friendly protocol

• 来源期刊: 科学通报(英文版)
• 学科: 化学
• 年，卷（期）: 2012,（18）
• 页码范围: 2273-2279
• 页数: 7页
• 分类号: O621.36
• 语种: 中文

摘要

A convenient,economical and green approach to the synthesis of 1H-indazolo[1,2-b]phthalazine-1,6,11-trione derivatives has been achieved via a one-pot protocol using phthalhydrazide,a cyclic-β-diketone and an aldehyde in the presence of a ceric ammonium nitrate catalyst in polyethylene glycol.The simple work up,mild conditions,excellent yields,inexpensive and non-toxic catalyst and simple solvent recyclability render this protocol both attractive and economically viable.