Primary CNS T-Cell Lymphoma: A Case Report on a Solitary Cerebellar Lesion and Review of Current Relevant Literature

• 作者: Aden McLaughlin Sharon Gabizon
• 来源期刊: 现代神经外科学进展(英文)
• 学科: 医学
• 关键词: PRIMARY CNS Lymphoma METHOTREXATE T-CELL
• 年，卷（期）: 2013,（2）
• 页码范围: 18-22
• 页数: 5页
• 分类号: R73

摘要

Primary central nervous system lymphoma of T-cell lineage (PCNSTL) is an extremely rare entity, with relatively few cases reported in the literature. Presented here is a case of a 44-year-old, HIV negative woman found to have a solitary cerebellar lesion following presentation to the Emergency Department with a fall. The lesion responded to emergent dexamethasone and was followed with serial MRI imaging, which continued to show lesion regression. The lesion was shown to have recurred on MRI 14 months post-presentation and found to be T-cell lymphoma following immunophenotyping and TCR gene rearrangement studies of tissue specimen obtained via excisional biopsy.