Yang et al [1] argue that sex and age are confounding factors in our study [2].However,by definition,they actually are not.Their sex difference argument does not have any influence on our result from a young Japanese male sample.In our article,we were interested in individual differences in reaction to unfairness observed in the ultimatum game.We were fully aware that sex and age are major factors to account for many brain functions and their disorders [3,4].We also understand that sex difference in personalities is a major research topic.Therefore,we focused on young male volunteers.In addition,to prevent young females from unnecessary radiation exposure,we recruited only male volunteers as a first step.Sex difference was already addressed as a limitation.Needless to say,it is highly recommended to test this ifa similar result could be observed in a female sample as well.