Does the autonomic nervous system contribute to the initiation and progression of prostate cancer?
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摘要:
In the July 12 issue of Science magazine,researchers from the Albert Einstein College of Medicine,the Mount Sinai School of Medicine,the Durham VA Medical Centre and Duke University published an degant study demonstrating that the sympathetic nervous system,acting through β2 and B3-adrenoceptors in the prostate,phys an important role in the initiation of prostate cancer,while the parasympathetic nervous system phys a role in the dissemination of tumourmetastases via M1 muscarinic receptors.These findings are significant because they indicate that receptors associated with the autonomic nervous system may be viable targets for prostate cancer therapy.