Spontaneous conception after autologous hematopoietic stem cell transplantation: a case report

• 来源期刊: 亚洲男性学杂志（英文版）
• 年，卷（期）: 2013,（1）
• 页码范围: 155-156
• 页数: 2页
• 语种: 英文
• DOI: 10.1038/aja.2012.119

摘要

Dear Editor, Allogeneic or autologous hematopoietic stem cell transplantation (HSCT) allows many patients with hematological malignancies to obtain prolonged survival and often disease cure.Autologous HSCT is particularly effective in acute promyelocytic leukemia (APL),a subtype of acute myeloid leukemia (AML) after relapse with conventional treatment.However,iatrogenic endocrine disturbances and reproductive failure are frequently-encountered late effects,which have a major impact on the quality of life.1 Conditioning regimens with total body irradiation (TBI) and intensive chemotherapy before autologous or allogeneic HSCT are known to cause permanent infertility,a risk that can be prevented by sperm banking.2