The mysterious origins of coronary vessels

• 来源期刊: 细胞研究（英文版）
• 年，卷（期）: 2013,（9）
• 页码范围: 1063-1064
• 页数: 2页
• 语种: 英文
• DOI: 10.1038/cr.2013.90

摘要

The origin of the coronary vessels remains a mystery.Here we discuss recent studies that address this puzzle,including new work by Tian et al.recently published in Cell Research. We face a growing epidemic of coronary vascular disease.Better understanding of the development of this unique vascular system will allow development of new treatment strategies.The origin of the coronary vessels has been a longstanding mystery.Classical anatomists proposed several potential sources for coronary vessels:the proepicardium (PE),the liver,the sinus venosus (SV) and the endocardium (Figure 1).Several recent reports have used sophisticated molecular and cell biological approaches to address this mystery,but have come to apparently contradictory conclusions.Tian et al.[1] use new lineage-tracing approaches to solve this puzzle,leading to new insights and new questions.