Losing stem cells in the aged skeletal muscle niche

• 来源期刊: 细胞研究（英文版）
• 年，卷（期）: 2013,（4）
• 页码范围: 455-457
• 页数: 3页
• 语种: 英文
• DOI: 10.1038/cr.2013.3

摘要

Why stem cell numbers decline with age is a major question in regenerative biology and medicine.Skeletal muscle has emerged as a powerful paradigm to address this issue.Recently,genetic and cell marking strategies were used to uncover a new and causal relationship between muscle stem cells and differentiated fibers that constitute their niche and provoke their loss.