GRA 14, a novel dense granule protein from Neospora caninum

• 来源期刊: 生物化学与生物物理学报（英文版）
• 年，卷（期）: 2013,（7）
• 页码范围: 607-609
• 页数: 3页
• 语种: 英文
• DOI: 10.1039/abbs/gmt036

摘要

Dense granule protein (GRA) is a secreted protein in Neospora caninum and Toxoplasma gondii,which plays an important role in forming parasitophorous vacuole (PV)[1-4].GRAs are thought to remodel and maintain the environment of the PV for intracellular survival and replication in T.gondii [5].The precise function of GRAs is still unknown [6-9].TgGRA14 protein is a new GRA protein that it is highly expressed and targeted to PV membrane and intravacuolar [5].However,the GRA14 of N.caninum (NcGRA14) has not been identified.