A Case of Autoimmune Hepatitis and Primary Biliary Cirrhosis Overlap Syndrome Treated with Chinese Herbs
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摘要:
Some patients present with overlapping features between disorders within the spectrum of autoimmune liver diseases,i.e.,autoimmune hepatitis (AIH),primary biliary cirrhosis (PBC),and primary sclerosing cholangitis (PSC),and are commonly classified as having an "overlap syndrome".The pathophysiological mechanisms underlying AIH-PBC overlap remain unclear.(1) Due to the lack of standardization and variations in the populations under study,the characteristics of these entities vary between studies and there have been few effective medical therapies for overlap syndrome up to now.(2'3) Here,we report a case of woman diagnosed as AIH-PBC overlap syndrome who had suboptimal response to single ursodeoxycholic acid (UDCA) or combination with immunosuppressive drug but had optimal response to Chinese herbs.