CEBPA-CEBPG axis as a novel promising therapeutic target in acute myeloid leukemia

• 来源期刊: 中国药理学报（英文版）
• 年，卷（期）: 2013,（2）
• 页码范围: 185-186
• 页数: 2页
• 语种: 英文
• DOI: 10.1038/aps.2012.191

摘要

Disruption of normal differentiation is an important link in tumorigenesis,but understanding the molecular mechanisms underlying this process is still limited.Acute myeloid leukemia (AML) is characterized by an accumulation of immature myeloid precursor cells in the bone marrow,which has been extensively used as a model for studying genetic/epigenetic regulation of differentiation and cancer progression.Inten