Loneliness is one of the central themes in the works of Nathanial Hawthorne,which,to some extent,is a reflection of Hawthorn’s keen sensitiveness to the existential anxiety of man in his times.The paper explores the theme of alienation that is exposed in the The House of the Seven of Seven Gables by making a careful analysis of morbid mentality of Hepzibah,which is mainly displayed in Hepzibah’s alienated feelings to the outside society and abnormal passion for Clifford.