Recent progress in autophagy

• 来源期刊: 细胞研究（英文版）
• 年，卷（期）: 2014,（1）
• 页码范围: 1-2
• 页数: 2页
• 语种: 英文
• DOI: 10.1038/cr.2014.1

摘要

Autophagy is a lysosome-based degradation process whose primary function is to degrade long-lived proteins and recycle cellular components.So far,3 types of autophagy have been documented,including macroautophagy,microautophagy and chaperone-mediated autophagy.Autophagy has been shown to degrade cargo in selective and noselective manners.In literature,the term "autophagy" usually indicates macroautophagy.Macroautophagy is characterized by the formation of double membrane vesicles termed autophagosomes.The biogenesis of autophagosomes is a subject of intensive study in recent years.