Review: Surgical Treatment of Type 2 Diabetes

• 作者: Alfonso López Ruiz Alicia Hernández Torres Ana Belén Hernández Cascales María ángeles Iba?ez María Dolores Hellín Gil Pedro Pujante Alarcón
• 来源期刊: 药理与制药(英文)
• 学科: 医学
• 关键词: DM2 BARIATRIC SURGERY GASTRIC BYPASS
• 年，卷（期）: 2014,（1）
• 页码范围: 24-29
• 页数: 6页
• 分类号: R73

摘要

In the last decades we have witnessed a significant increase in the incidence of type 2 diabetes mellitus, and obesity in parallel. So 90% of patients with Diabetes Mellitus type 2 (DM2) are obese. Changes in lifestyle (diet and exercise), behavioral therapies or the use of certain anti-obesity drugs have shown a limited effect and are not maintained over time. Currently, bariatric surgery is the most effective anti-obesity treatment, which is durable and resolves associated comorbidities. The surgical treatment of obesity for the modification of the anatomy of the digestive system is to produce gastric capacity constraints alone or associate with varying degrees of intestinal malabsorption and reduce body weight, improve and maintain the comorbidities associated weight loss by reduced food intake alone or in combination with malabsorption of this. The development of these surgical techniques has occurred in stages. With these techniques, setting to bariatric surgery is an effective, safe and proven procedure for the treatment of obesity and its complications especially DM2, as their post surgery referral mechanisms provide us with information for potential therapeutic treatment aimed at optimizing the control DM2 patients metabolic obese. In this review, we expose the evidence in treatment of DM2 with bariatric surgery and the actual hypothesis trying to explain how it is possible.