Synthesis and X-Ray Structure of New Anticancer Nucleosides Based on 1-((2-Hydroxyethoxy)methyl)-5-(phenylthio)-1H-1,2,4-triazole-3-carboxamide

• 作者: Dehua Zhang Guanghui Tian Hongguang Ge Yang Liu Yulong Lei
• 来源期刊: 结晶过程及技术期刊(英文)
• 学科: 化学
• 关键词: ANTICANCER NUCLEOSIDES TRIAZOLE NUCLEOSIDES Excellent YIELDS
• 年，卷（期）: 2014,（3）
• 页码范围: 135-139
• 页数: 5页
• 分类号: O6

摘要

A pair of new anticancer nucleosides based on 1,2,4-triazole nucleosides and 1-((2-hydroxyethoxy) methyl)-5-(phenylthio)-1H-1,2,4-triazole-3-carboxamide have been synthesized, and have given the corresponding products in excellent yields. Its structures and conformations were confirmed by single crystal X-ray diffraction.