Current Treatment of DCIS

• 作者: Christina Choy Kefah Mokbel
• 来源期刊: 癌症治疗(英文)
• 学科: 医学
• 关键词: EARLY BREAST CANCER DCIS BREAST CANCER DIAGNOSIS and TREATMENT
• 年，卷（期）: 2014,（2）
• 页码范围: 179-181
• 页数: 3页
• 分类号: R73

摘要

Abstract: Ductal carcinoma in-situ DCIS is a heterogeneous entity in breast neoplasm with unpredictable biological behavior. This poses challenge in the management of DCIS. Various trials on DCIS have shown good outcome with integral treatment of adequate surgery, radiotherapy and hormonal therapy. Identification of subgroup of DCIS for radiotherapy and hormonal therapy could improve recurrence rate, contralateral tumours incidence and perhaps overall survival. Various risk score calculations could help to direct radiotherapy and hormonal treatment verses surgery alone and to avoid over treatment. Oncotype DX assay could be a new way of risk calculation to direct types of DCIS treatment. The recent increased use of MRI could increase the detection of DCIS and a more accurate extent of disease estimation. This article is a summary of major literatures and major trials result for DCIS.