Quantitative magnetic resonance imaging of the fetal brain in utero: Methods and applications

• 作者: Anat Biegon Chen Hoffmann
• 来源期刊: 世界放射学杂志：英文版（电子版）
• 学科: 医学
• 关键词: FETAL brain FETAL MAGNETIC RESONANCE IMAGING FETAL MAGNETIC RESONANCE spectroscopy FETAL APPARENT diffusion coefficients FETAL functional MAGNETIC RESONANCE IMAGING CORTICAL development
• 年，卷（期）: 2014,（8）
• 页码范围: 523-529
• 页数: 7页
• 分类号: R445.2

摘要

Application of modern magnetic resonance imaging(MRI) techniques to the live fetus in utero is a relatively recent endeavor. The relative advantages and disadvantages of clinical MRI relative to the widely used and accepted ultrasonographic approach are the subject of a continuing debate; however the focus of this review is on the even younger field of quantitative MRI as applied to non-invasive studies of fetal brain development. The techniques covered under this header include structural MRI when followed by quan-titative(e.g., volumetric) analysis, as well as quantita-tive analyses of diffusion weighted imaging, diffusion tensor imaging, magnetic resonance spectroscopy and functional MRI. The majority of the published work re-viewed here reflects information gathered from normal fetuses scanned during the 3rd trimester, with relatively smaller number of studies of pathological samples including common congenital pathologies such as ven-triculomegaly and viral infection.