Where cell fate conversions meet Chinese philosophy

• 来源期刊: 细胞研究（英文版）
• 年，卷（期）: 2014,（10）
• 页码范围: 1162-1163
• 页数: 2页
• 语种: 中文
• DOI: 10.1038/cr.2014.93

摘要

Accumulating evidence indicates that the mesenchymal-epithelial transition (MET) and epithelialmesenchymal transition (EMT) are basic mechanisms for cell fate conversion and may help us understand both physiologic and pathologic processes such as development and carcinogenesis.Here,we further suggest that mammalian cells fall into two grand divisions,mesenchymal or epithelial;interconversions between these two grand divisions through EMT/MET resonate with some ancient Chinese philosophic ideas.