More attention should be paid to the treatment of male infertility with drugs—testosterone: to use it or not?
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摘要:
Testosterone replacement is strictly contraindicated for the treatment of male infertility was the advanced view from the ‘2013 European Association of Urology (EAU) guidelines on male infertility',and this view brings extensive concern and questions.Although sufficient numbers of well-performed and controlled clinical trials that provide evidence supporting drug treatment of male infertility are not available at present,the opportunity to prove that these drugs are effective should not be prevented,and rigorous examination of drug therapy should be encouraged and strengthened.Therefore,I believe the aboveconclusion in the EAU guidelines is poorly conceived.
While reading the ‘2013 European Association of Urology (EAU) guidelines on male infertility',I found some information that was difficult to interpret and acknowledge.According to the guidelines,‘Testosterone replacement is strictly contraindicated for the treatment of male infertility.Grade of Recommendation is A'1 I was confused by the presentation of the new EAU guidelines for male infertility.Although the related references were listed in the 2013 EAU guidelines on male infertility,I propose that the objective facts that are described in the references should not serve as evidence for a class A (the highest level) recommendation and that the notes on the recommendation level that are given in the guidelines are not ‘upgraded' following panel consensus.This statement further confused me.After discussing and analyzing this information with some andrological experts in China and abroad,I decided to express my perspectives on this problem.