Prospects for clinically relevant epigenetic tests in the andrology laboratory

• 来源期刊: 亚洲男性学杂志（英文版）
• 年，卷（期）: 2014,（5）
• 页码范围: 782
• 页数: 1页
• 语种: 中文
• DOI: 10.4103/1008-682X.125415

摘要

The review published by Kl(a)iver and Gromoll1 is a timely reminder of the ever-changing landscape of the dinical andrology laboratory as well as the limitations of current approaches to properly diagnose and treat male infertility.In a variety of disciplines,the clinical relevance of epigenetic status is becoming increasingly apparent.In this paper,the authors review the various studies that have evaluated the epigenetics (primarily DNA methylation) of sperm in the context of infertility,and they discuss the potential value of sperm epigenetic analysis in the workup of idiopathic male infertility.