Is number of chiasmata an etiological factor of male infertility?

• 来源期刊: 亚洲男性学杂志（英文版）
• 年，卷（期）: 2014,（6）
• 页码范围: 920
• 页数: 1页
• 语种: 中文
• DOI: 10.4103/1008-682X.136442

摘要

Azoospermia and/or severe oligozoospermia can be treated as principal factors of male infertility.Specifically,azoospermia that stands for 1％ of males and 10％ of infertile male population has been mostly unexplained (idiopathic),however,it is suspected for its genetic and/or molecular background? Pertaining to molecular background of severe oligo-astheno-teratozoospermia (OAT)-the meiotic abnormalities are suspected to reach almost 20 ％.2 Therefore,this potentially addresses a significant number of cases that could find a possible etiological factor.Meiotic abnormalities as the authors point out encompass combination of anomalies in the process of pairing,synapsis,recombination,chromosome segregation and failures in controlling mechanisms-number of chiasma (diminished) could be one of the reasons.