Transition metal mediated functionalization of o-carboranes

• 来源期刊: 中国科学:化学（英文版）
• 年，卷（期）: 2014,（8）
• 页码范围: 1061-1063
• 页数: 3页
• 语种: 中文
• DOI: 10.1007/s11426-014-5166-z

摘要

Carboranes are a class of boron hydride clusters in which one or more of the BH vertices are replaced by CH units.Unlike small boranes,carboranes are kinetically and thermodynamically very stable as well as relatively chemically inert,which are often called three-dimensional relatives of benzenes.They are finding many applications in medicine as boron neutron capture therapy (BNCT) agents,in nanomaterials/supramolecular design as building blocks,and as ligands for transition metals [1].However,their unique structures make derivatization difficult,which limits their application scope.To this end,there is a need to develop new methodologies for the functionalization of carboranes.In view of the widespread use of transition metals in synthetic chemistry,we initiated a research program to develop transition metal-mediated/catalyzed synthetic methods for cage C-H/B-H functionalization of carboranes.This short article highlights the recent development and addresses the problems in this growing area.