Crosstalk between mitochondria and peroxisomes

• 作者: Fran?oise Le Borgne Jean Demarquoy
• 来源期刊: 世界生物化学杂志：英文版（电子版）
• 学科: 生物学
• 关键词: PEROXISOME MITOCHONDRION BETA-OXIDATION Reactive o
• 年，卷（期）: 2015,（4）
• 页码范围: 301-309
• 页数: 9页
• 分类号: Q244

摘要

Mitochondria and peroxisomes are small ubiquitous organelles. They both play major roles in cell metabolism,especially in terms of fatty acid metabolism,reactive oxygen species(ROS) production,and ROS scavenging,and it is now clear that they metabolically interact with each other. These two organelles share some properties,such as great plasticity and high potency to adapt their form and number according to cell requirements. Their functions are connected,and any alteration in the function of mitochondria may induce changes inperoxisomal physiology. The objective of this paper was to highlight the interconnection and the crosstalk existing between mitochondria and peroxisomes. Special emphasis was placed on the best known connections between these organelles:origin,structure,and metabolic interconnections.