Flexible Polyimide Microelectrodes Array for Transcorneal Electrical Stimulation

• 作者: Félix Gil Carrasco Fidel W. Pérez-Tovar Jorge Santiago Amaya Luis Ni?o de-Rivera
• 来源期刊: 生物医学工程(英文)
• 学科: 医学
• 关键词: MICROELECTRODES FLEXIBLE Polymide MICROELECTRODES Transcorneal ELECTRICAL STIMULATION
• 年，卷（期）: 2015,（8）
• 页码范围: 544-554
• 页数: 11页
• 分类号: R73

摘要

The relationship between the parameters of Transcorneal Electrical Stimulation (TES) and its neuro-protective effect of TES on axotomised Retinal Ganglion Cells (RGCs) is still unclear. This work discusses the design strategy of a new non conventional TES stimulator, the micro fabrication processes and characterization of an array of MEMS microelectrodes over a flexible polymer layer substrate to stimulate the human cornea. The micro-array of electrodes, over a flexible smooth biocompatible polyimide substrate, fine tunes the curvature of the cornea. This tool can help researchers to define the optimal electric stimulation parameters required in TES.