Generation of monoclonal antibodies against n-3 fatty acid desaturase
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摘要:
Dear Editor:
Omega-3 polyunsaturated fatty acids (n-3 PUFAs) are essential fatty acids for normal cellular functions and have been used for prevention and treatment of many diseases,including coronary heart disease,diabetes,and cancers[1-3].n-3 PUFAs and n-6 PUFAs have been shown to decrease and increase the severity of several human diseases,respectively[4].Unfortunately,mammals have no enzymes to synthesize n-6 and n-3 fatty acids.