Effect of Soy Bean Isoflavon on Lipid Accumulation in 3T3-L1 Adipocytes

• 作者: Noriko Yoshimura Teruhiko Matsushima Yuumi Koseki
• 来源期刊: 生物科学与医学(英文)
• 学科: 医学
• 关键词: OBESITY ADIPOCYTE GENISTEIN RESVERATROL
• 年，卷（期）: 2015,（9）
• 页码范围: 52-54
• 页数: 3页
• 分类号: R73

摘要

Several nutrition and food ingredients are supposed to have beneficial effects, but precise cell biological mechanism has not been elucidated. Among food ingredients, polyphenols such as soy bean isoflavon genistein and wine resveratrol have been reported to have effects on lipid metabolism and cardiovacular diseases (1). In order to elucidate the effect of genistein on obesity, we cultured adipocyte and observed of genisten to lipid accumulation in cells. Triglyceride accumulation was suppressed by genistein when it was added at the time of differentiation but not when added after differentiation. Genistein is considered to suppress lipid accumulation by suppressing the differtiation of adipocytes.