An Evans Syndrome Case Expressing Anti-Jk<sup>a</sup>Autoantibody under Condition of Primary IgA Immunodeficiency

• 作者: Akira Hayakawa Ayumi Tani Hironobu Minami Ikuko Kubokawa Ikuyo Hayakawa Makoto Hashimoto Nobuyuki Yamamoto Satoshi Hirase Takeshi Kato Takeshi Mori Takeshi Sugimoto Tomoko Yanai
• 来源期刊: 临床医学国际期刊(英文)
• 学科: 医学
• 关键词: Anti-Jka AUTOANTIBODY EVANS Syndrome IGA IMMUNODEFICIENCY
• 年，卷（期）: 2015,（7）
• 页码范围: 496-499
• 页数: 4页
• 分类号: R5

摘要

Autoimmune haemolytic anaemia is a haemolytic disease resulting from an autoimmune reaction to the surface of red blood cells. A part of autoantibody is known to react with the blood type antigen. This is the case of a 14 years old female with Evans syndrome in which autoimmune haemolysis may cause from anti-Jka autoantibody reaction. As this case is complicated with primary IgA immunodeficiency syndrome, anti-Jka autoantibody may occur under the condition of primary immunodeficiency status, in which autoantibody production is accelerated. Considering the co-occurrence of autoimmune haemolytic anaemia and primary IgA immunodeficiency syndrome, analysis focusing on specificity for red blood cells antigens will be required in IgA immunodefi-ciency syndrome patients.