Editorial

• 来源期刊: 药学学报（英文版）
• 年，卷（期）: 2015,（2）
• 页码范围: 89
• 页数: 1页
• 语种: 中文

摘要

Bile acids have been traditionally viewed as detergent molecules involved in the solubilization and absorption of lipids and lipidsoluble vitamins from the intestines.However, as a result of intensive research over the past two decades, bile acids are now viewed as endocrine signaling molecules that activate specific nuclear receptors and G-protein coupled receptors regulating nutrient metabolism in the liver and intestines.The year 2015 marks the 20-year anniversary of the cloning and discovery offarnesoid X receptor (NR4H1;FXR).