Serum IL-1β and IL-18 correlate with ESR and CRP in multidrug-resistant tuberculosis patients

• 来源期刊: 生物医学研究杂志（英文版）
• 学科: 医学
• 年，卷（期）: 2015,（5）
• 页码范围: 426-428
• 页数: 3页
• 分类号: R183.3
• 语种: 中文
• DOI: 10.7555/JBR.29.20150077

摘要

Dear Editor: The emergence of multidrug-resistant tuberculosis (MDR-TB) is bringing new challenges.MDR-TB is caused by Mycobacterium tuberculosis (M.tuberculosis) that is resistant to isoniazid and rifampicin, with or without resistance to other anti-tuberculosis drugs.Approximately 450,000 people developed MDR-TB worldwide in 2012 and an estimated 170,000 people died from the disease[1].Bacterial burden is not strictly correlated with disease progression, and several hallmarks of severe tuberculosis suggest that insufficiently controlled inflammation plays an important role in pathogenesis[2].