Characterization and target identification of a DNA aptamer that labels pluripotent stem cells

• 来源期刊: 细胞研究（英文版）
• 年，卷（期）: 2015,（3）
• 页码范围: 390-393
• 页数: 4页
• 语种: 中文
• DOI: 10.1038/cr.2015.7

摘要

Dear Editor, Aptamers are short stretches of nucleotides or amino-acid residues that are engineered to bind to various targets,from small chemicals to large proteins and live cells [1-5].Aptamers are normally selected through a process called systematic evolution of ligands by exponential enrichment (SELEX),in which aptamers are selected from a random library of oligonucleotides or peptides against a target through repeated rounds of selection and amplification [2].