Probing single protein with electron spin resonance in combination with shallow nitrogen vacancy

• 来源期刊: 中国科学:化学（英文版）
• 年，卷（期）: 2015,（5）
• 页码范围: 833
• 页数: 1页
• 语种: 中文
• DOI: 10.1007/s11426-015-5416-8

摘要

Proteins are the main power of life with vast functions within living organisms,such as assembling the cell structure,catalyzing metabolic reactions,transcribing and replicating DNA,responding to stimuli,and transporting molecules from one location to another.The proteins' functions are closely related to their sequence,conformation and interaction network.For understanding the mechanism of protein function,it is essential to visualize the single protein at work,solve the three dimensional structure at atomic resolution,and address the partnership and dynamics of protein interaction.The analytical techniques or tools are fundamental for achieving such goals.In the past decades,tremendous efforts have been made in order to develop new methods with ultra sensitivity and resolution.