Krill: a novel gene that links defective ribosome biogenesis to impaired hematopoiesis through excessive autophagy

• 来源期刊: 科学通报（英文版）
• 年，卷（期）: 2015,（17）
• 页码范围: 1547-1548
• 页数: 2页
• 语种: 中文
• DOI: 10.1007/s11434-015-0877-x

摘要

The ribosome is an ancient and conserved molecular machine responsible for translating mRNA into protein in all known organisms.The eukaryotic ribosome is composed of ～ 80 ribosomal proteins (RPs) and four ribosomal RNAs (rRNAs).These RNA and protein components are assembled within the nucleolus into the small 40S and large 60S subunits of the ribosome,through a process termed ribosome biogenesis.