Using 3dRPC for RNA-protein complex structure prediction

• 来源期刊: 生物物理学报
• 年，卷（期）: 2016,（5）
• 页码范围: 95-99
• 页数: 5页
• 语种: 中文
• DOI: 10.1007/s41048-017-0034-y

摘要

3dRPC is a computational method designed for three-dimensional RNA-protein complex structure prediction.Starting from a protein structure and a RNA structure,3dRPC first generates presumptive complex structures by RPDOCK and then evaluates the structures by RPRANK.RPDOCK is an FFT-based docking algorithm that takes features of RNA-protein interactions into consideration,and RPRANK is a knowledgebased potential using root mean square deviation as a measure.Here we give a detailed description of the usage of 3dRPC.The source code is available at http://biophy.hust.edu.cn/3dRPC.html.