What is the best way to manage screening for infections and vaccination of inflammatory bowel disease patients?

• 作者: Alessandro Armuzzi Alfredo Papa Carla Felice Daniela Pugliese Gianluca Andrisani Luisa Guidi Manuela Marzo
• 来源期刊: 世界胃肠药理与治疗学杂志：英文版（电子版）
• 学科: 医学
• 关键词: Inflammatory bowel disease OPPORTUNISTIC INFECTIONS IMMUNOMODULATORS CORTICOSTEROIDS ANTI-TUMOR necrosis factor agents
• 年，卷（期）: 2016,（3）
• 页码范围: 387-396
• 页数: 10页
• 分类号: R574

摘要

The use of biological agents and immunomodulators for inflammatory bowel disease(IBD) is associated with an increased risk of opportunistic infections, in particular of viral or bacterial etiology. Despite the existence of international guidelines, many gastroenterologists have not adopted routine screening and vaccination in those patients with IBD, which are candidate for biologic therapy. Available strategies to screen, diagnose and prevent bacterial and viral infections in patients with IBD prior to start biological therapy are discussed in this review.