The molecular mechanisms of the mechanosensitive Piezo1 ion channel
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摘要:
Supported by the National Natural Science Foundation of China and the Ministry of Science and Technology of China,the research group led by Prof.Xiao Bailong (肖百龙) at the School of Pharmaceutical Sciences,Tsinghua-Peking Joint Center for Life Sciences,and IDG/McGovern Institute for Brain Research,Tsinghua University,published a research article entitled "Ion Permeation and Mechanotransduction Mechanisms of Mechanosensitive Piezo Channels" in Neuron (2016,89(6):1248-63),providing important insights into the ion-conducting and mechanotransduction mechanisms of an evolutionarily conserved and physiologically important class of ion channels.