Autophagy: a stumbling block of androgen inhibition to treat benign prostatic hyperplasia or prostate cancer
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摘要:
Dear Editor,
Benign prostatic hyperplasia (BPH) and prostate cancer (PCa) are the two most common prostatic disorders affecting elderly males and represent significant burdens for health-care systems worldwide.1 BPH and PCa exhibit important differences in terms of histology and localization,and to date,no causal relationship between the two prostatic diseases has been demonstrated,but BPH and PCa indeed share traits such as androgen-dependent growth and response to hormonal therapy.2