Efficient asymmetric catalytic synthesis of antidepressant escitalopram

• 来源期刊: 中国科学基金（英文版）
• 年，卷（期）: 2016,（3）
• 页码范围: 35
• 页数: 1页
• 语种: 英文

摘要

With the support by the National Natural Science Foundation of China and the Thousand Talents Youth Program,the research team led by Prof.Tang Wenjun (汤文军) at the State Key Laboratory of Bio-organic and Natural Products Chemistry,Shanghai Institute of Organic Chemistry,Chinese Academy of Sciences,and Prof.Deng Weiping (邓卫平) at the School of Pharmacy,East China University of Science and Technology,reported an efficient asymmetric catalytic synthesis of antidepressant escitalopram by developing a highly enantioselective rhodium-catalyzed addition of aryl boroxines to simple aryl ketones,which was published in Angew Chem Int Ed (2016,55:4527-4531).