As you can see from the title,we try to provide a brief analysis of ambiguity of words’ meaning in translation practice,namely,what is ambiguity of a meaning of a word and how it is caused,and how it affects translation.What effective methods are available to help us achieve a successful translation? Although a perfect solution for the problems presented by the ambiguity of words’ meaning is difficult to find,we try to do what it can to contribute to the solution and draw people’s attention to those problems.