Novel Diazole/Triazole and Dibenzothiophene Dioxide Containing Pentacyclic Systems with Promising Biological Activities

• 作者: Elene Kalandia Giorgi Phalavadishvili Mamuka Maisuradze Manana Matnadze Nana Gakhokidze Sofo Tskhvitaia
• 来源期刊: 有机化学国际期刊(英文)
• 学科: 化学
• 关键词: DIBENZOTHIOPHENE Dioxide IMIDAZOLE TRIAZOLE Pentacyclic Systems
• 年，卷（期）: 2017,（1）
• 页码范围: 34-41
• 页数: 8页
• 分类号: O6

摘要

The aim of the current work is to synthesize the new heterocyclic pentacyclic condensed systems that combine benzothiophen and benzimidazole/triazole into one molecule. The dibenzothiophene was taken as an initial compound and by consistent “extension” was annihilated the imidazole and triazole nucleuses. As a result two new pentacyclic systems were produced: 3H-, 7H-diimidazole[4,5-b][5,4-g] dibenzothiophene-5,5-dioxide and 3H-, 7H-ditriazole[4,5-b][5,4-g] dibenzothiophene-5,5-dioxide with the promising antimi-crobial activity. Their spectral characteristics were studied.