Endoscopic submucosal dissection for small submucosal tumors of the rectum compared with endoscopic submucosal resection with a ligation device

• 作者: Daisuke Murakami Hideaki Harada Kenji Hayasaka Ryotaro Nakahara Satoshi Suehiro Shigetaka Tounou Takanori Shimizu Yasunaga Miyama Yasushi Katsuyama
• 来源期刊: 世界胃肠内镜杂志：英文版（电子版）
• 学科: 医学
• 关键词: 平滑肌瘤 脂肪瘤 直肠 Submucosal 肿瘤 有一台结扎设备的内视镜的 submucosal 切除术 内视镜的 submucosal 解剖 良性肿瘤肿瘤
• 年，卷（期）: 2017,（2）
• 页码范围: 70-76
• 页数: 7页
• 分类号: R735.37

摘要

AIM To evaluate the efficacy and safety of endoscopic submucosal dissection(ESD) for small rectal submucosal tumors(SMTs).METHODS Between August 2008 and March 2016, 39 patients were treated with endoscopic submucosal resection with a ligation device(ESMR-L)(n = 21) or ESD(n = 18) for small rectal SMTs in this study. Twenty-five lesions were confirmed by histological evaluation of endoscopic biopsy prior to the procedure, and 14 lesions were not evaluated by endoscopic biopsy. The results for the ESMR-L group and the ESD group were retrospectively compared, including baseline characteristics and therapeutic outcomes.RESULTS The rate of en bloc resection was 100% in both groups. Although the rate of complete endoscopic resectionwas higher in the ESD group than in the ESMR-L group(100% vs 95.2%), there were no significant differences between the two groups(P = 0.462). In one patient in the ESMR-L group with a previously biopsied tumor, histological complete resection with a vertical margin involvement of carcinoid tumor could not be achieved, whereas there was no incomplete resection in the ESD group. The mean length of the procedure was significantly greater in the ESD group than in the ESMR-L group(14.7 ± 6.4 min vs 5.4 ± 1.7 min, P < 0.05). The mean period of the hospitalization was also significantly longer in the ESD group than in the ESMR-L group(3.7 ± 0.9 d vs 2.8 ± 1.5 d, P < 0.05). Postoperative bleeding was occurred in one patient in the ESMR-L group.CONCLUSION Both ESMR-L and ESD were effective for treatment of small rectal SMTs. ESMR-L was simpler to perform than ESD and took less time.