This paper considers the condition numbers of a semi-simple eigenvalue of quadratic eigenvalue problem.Based on analytic perturbation of semi-simple eigenvalue of regular quadratic eigenvalue problem,different condition numbers of semi-simple eigenvalue are introduced.The computable expressions of introduced condition numbers are derived.The condition numbers defined in this paper can measure not only the worst case perturbation of the multiple eigenvalue,but also the corresponding sensitivities of different eigenvalues splitted from the semi-simple eigenvalue.