Two new steroidal saponins isolated from Anemarrhena asphodeloides

• 来源期刊: 中国天然药物
• 学科: 医学
• 年，卷（期）: 2017,（3）
• 页码范围: 220-224
• 页数: 5页
• 分类号: R284
• 语种: 英文
• DOI: 10.3724/SP.J.1009.2017.00220

摘要

Two new steroidal saponins,named timosaponin P (1) and timosaponin Q (2),were isolated from the rhizome parts of Anemarrhena asphodeloides Bunge using various chromatographic methods.Their structures and absolute configurations were elucidated by a combination of spectroscopic and spectrometric data,including 1 D,2D NMR,HR-ESI-MS and ECD calculations,and this is the first time the absolute configuration of C-23 of steroidal saponin was confirmed by ECD calculations.