Nine compounds from the root bark of Lycium chinense and their anti-inflammatory activities

• 来源期刊: 药学学报（英文版）
• 关键词: Lycium chinense Lyciumlignan D Lyciumphenyl propanoid A Structure elucidation Anti-inflammatory effect
• 年，卷（期）: 2017,（4）
• 页码范围: 491-495
• 页数: 5页
• 语种: 英文

摘要

Two new compounds,named lyciumlignan D (1) and lyciumphenyl propanoid A (2),along with seven known compounds,were isolated from the root bark of Lyciurn chinense.Their structures were elucidated using spectroscopic data (UV,IR,HR-ESI-MS,1D and 2D NMR,CD),as well as by comparison with those of the literature.Compounds 3-9 were isolated from this genus for the first time.In the in vitro assay,compounds 3,6,and 7 exhibited stronger anti-inflammatory effects than the positive control curcumin at a concentration of 10 μmol/L.