Deanxit relieves symptoms in a patient with jackhammer esophagus: A case report

• 作者: Chun-Ling Huang Dang Huang Guo-Wen Zuo Jin-Ying Li Lie-Xin Liang Wen-Huan Zhang
• 来源期刊: 世界胃肠内镜杂志：英文版（电子版）
• 学科: 医学
• 年，卷（期）: 2017,（12）
• 页码范围: 590-593
• 页数: 4页
• 分类号: R571

摘要

Jackhammer(hypercontractile) esophagus presents with dysphagia and chest pain. Current treatments are limited. We describe a 60-year-old man who presented with dysphagia, chest pain and heartburn for a period of 1 year. His workup showed Barrett’s esophagus on endoscopy and high-resolution manometry demonstrated jackhammer esophagus with esophagogastric junction outflow obstruction. The patient was treated with proton pump inhibitor and nifedipine but without resolution of his symptoms. He was followed up to assess the efficacy of treatment with deanxit(flupentixol + melitracen). Dysphagia and chest pain resolved during the therapeutic trial and efficacy was maintained on maintenance treatment without troublesome side effects.