Cycloartane triterpenoid and its glucoside isolated from Cassia occidentalis

• 来源期刊: 中国天然药物
• 学科: 医学
• 年，卷（期）: 2017,（12）
• 页码范围: 950-954
• 页数: 5页
• 分类号: R284.2|R917
• 语种: 英文
• DOI: 10.3724/SP.J.1009.2017.00950

摘要

In the present study,one new cycloartane triterpenoid,named cycloccidentalic acid C (1) and its glucoside,cycloccidentaliside Ⅵ (2) were isolated from the whole plant of Cassia occidentalis.Their structures were elucidated by a combinational analyses of 1D and 2D NMR data and HRMS.Compound 2 showed modest anti-HIV-1 activity with EC50 value of 1.44 μmol·L-1 and TI (Therapeutic Index) value of 15.59.