Low-frequency blood oxygen level-dependent fluctuations in the brain white matter: more than just noise
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摘要:
The spontaneous activity of the blood oxygen level-dependent (BOLD) signal has been demonstrated as a promising way for understanding how the brain intrinsically organized.However,most of these studies focused solely on the spontaneous activity in gray matter (GM) and not on white matter (WM).This is likely because low-frequency BOLD fluctuations (LFBFs) in GM are related to postsynaptic potential,while the physiological significance of fluctuations in WM is largely unknown [1].Recently,there are increasing evidences implicating the neurobiological significance of LFBFs in WM [2-4].Here,we further investigated this issue from the perspective of energy consumption.