Human parvovirus B19-associated hematopathy in HIV disease:need for clinicopathological revisit

• 来源期刊: 生物医学研究杂志（英文版）
• 学科: 医学
• 年，卷（期）: 2018,（1）
• 页码范围: 1-2
• 页数: 2页
• 分类号: R512.91
• 语种: 英文

摘要

Persons living with HIV infection occasionally suffer from anemia due to varying causes.These include the use of zidovudine,malnutrition especially vitamin B12 and iron deficiency,opportunistic infections by Mycobacterium tuberculosis,Pneumocystis jiroveci,and direct hematological effects of HIV infection itself within the marrow microenvironment.Persistent Parvovirus B 19 (B 19V) infection is a clinically important and treatable etiology of anemia in HIV-infected persons.B19V is known to show singular tropism and lytic infection of erythroid progenitor cells which may consequently result in transient red cell aplasia (TRCA) and chronic anemia.