Susceptibility weighted imaging:Clinical applications and future directions

• 作者: Ahmet Mesrur Halefoglu David Mark Yousem
• 来源期刊: 世界放射学杂志：英文版（电子版）
• 学科: 医学
• 关键词: QUANTITATIVE SUSCEPTIBILITY mapping Brain ISCHEMIA Magnetic RESONANCE IMAGING SUSCEPTIBILITY WEIGHTED IMAGING
• 年，卷（期）: 2018,（4）
• 页码范围: 30-45
• 页数: 16页
• 分类号: R

摘要

Susceptibility weighted imaging(SWI)is a recently developed magnetic resonance imaging(MRI)technique that is increasingly being used to narrow the differential diagnosis of many neurologic disorders.It exploits the magnetic susceptibility differences of various compounds including deoxygenated blood,blood products,iron and calcium,thus enabling a new source of contrast in MR.In this review,we illustrate its basic clinical applications in neuroimaging.SWI is based on a fully velocity-compensated,high-resolution,three dimensional gradientecho sequence using magnitude and phase images either separately or in combination with each other,in order to characterize brain tissue.SWI is particularly useful in the setting of trauma and acute neurologic presentations suggestive of stroke,but can also characterize occult low-flow vascular malformations,cerebral microbleeds,intracranial calcifications,neurodegenerative diseases and brain tumors.Furthermore,advanced MRI post-processing technique with quantitative susceptibility mapping,enables detailed anatomical differentiation based on quantification of brain iron from SWI raw data.