Ⅰ-BAR protein IRSp53 regulates clathrin-independent endocytosis in a biphasic manner
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摘要:
Endocytosis is a fundamental cellular activity that plays crucial roles in a variety of biological processes,including nutrient uptake,signal transduction,immune response,morphogenesis,neuro-transmission,cell migration and tissue development [1-3].Endocytosis has been classified into two subtypes:the well-defined clathrin-dependent endocytosis (CDE) and the more recently identiffed clathrin-independent endocytosis (CIE) [3].